Weight Loss Journey Estimator
A visual projection of what GLP-1 therapy typically looks like over ~68 weeks, based on mean total body weight loss reported in STEP-1 (semaglutide) and SURMOUNT-1 (tirzepatide). Outcomes vary by individual.
Based on mean total body weight loss in STEP-1 (semaglutide) and SURMOUNT-1 (tirzepatide). Individual outcomes vary widely.
- Week 4Titration
Lowest dose; appetite begins to shift. Expect 1–2% drop.
- Week 12Early loss
Steady weekly loss. Side effects typically peak then fade.
- Week 24Mid-cycle
Loss slows but compounds. Body composition shifts visibly.
- Week 40Approaching plateau
Weekly loss thins out. Habits and protein matter most.
- Week 68New setpoint
Mean clinical-trial endpoint. Maintenance phase begins.
Most people stall by month 6–9. The trajectory typically resumes with steady protein intake, resistance training, and time at a stable dose.
Lower A1C, smaller waist, better sleep, reduced food noise, and improved energy often arrive before the scale catches up.
Estimator is educational only. It is not a clinical prediction and does not replace guidance from your prescriber.